MUSE7 was identified in a forward genetic screen to identify snc1 enhancers using a mos4 snc1 background. muse7 mos4 snc1 plants are morphologiclly similar to snc1 plants with slightly twisted leaves. The triple mutant also shows PR gene activation and enhanced resistance to pathogens, like the snc1 single mutant. It is a single copy gene conserved in plants and metazoans.MUSE7 encodes an evolutionarily conserved putative kinase substrate of unknown function that affects the accumulation of NLR proteins.
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