Encodes a phloem-specific iron transporter that is essential for systemic iron signaling and redistribution of iron and cadmium. It loads iron into the phloem, facilitates iron recirculation from the xylem to the phloem, and regulates both shoot-to-root iron signaling and iron redistribution from mature to developing tissues.
Transcription of At4g16370 is upregulated in Mn-, iron-, and copper-deficient plants. At4g16370 can rescue yeast CTR1 (copper deficient) and Smf1 (manganese deficient) mutants, suggesting a function in metal transport.