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Search results 1 to 100 out of 2174 for S-Adenosyl-L-methionine (SAMe)

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Type Details Score
Protein
Q9SCW2_ARATH | Q9SCW2
Organism . Name: Arabidopsis thaliana
Length: 51  
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Ontology Term
- | S-adenosyl-L-methionine
Description: Protein which binds at least one S-adenosyl-L-methionine (SAM), or protein whose function is SAM-dependent. S-adenosyl-L-methionine, a conjugate of the nucleotide adenosine and the amino acid methionine, is a substrate/cofactor in numerous enzyme-catalyzed reactions Enzymatic reactions that involve interactions of proteins with S- adenosyl-L-methionine include transfer of methyl, thiomethyl, aminoalkyl and adenosyl groups. It not only provides methyl groups to be transferred in numerous biological reactions, but also acts as a precursor in the biosynthesis of polyamines and metal ion chelating compounds. It is also a source of catalytic 5'-deoxyadenosyl radicals produced as reaction intermediates by a superfamily of radical enzymes. It is also involved in decarboxylation reactions
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]
Type: synonym
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine decarboxylase activity
Type: synonym
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine carboxy-lyase activity
Type: synonym
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine synthetase activity
Type: synonym
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)
Type: synonym
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine methylthioadenosine-lyase activity
Type: synonym
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Ontology Term Synonym
Ontology Term Synonym
Name: S-adenosyl-L-methionine alkyltransferase (cyclizing)
Type: synonym
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GO Term
GO:0004014 | adenosylmethionine decarboxylase activity
Description: Catalysis of the reaction: S-adenosyl-L-methionine + H+ = S-adenosylmethioninamine + CO2.
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GO Term
GO:0015805 | S-adenosyl-L-methionine transport
Description: The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:1904047 | S-adenosyl-L-methionine binding
Description: Binding to S-adenosyl-L-methionine.
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Gene
AT3G43210 | locus:2084701 | TES | TETRASPORE
Length: 5430  
Chromosome Location: Chr3: 15190786-15196215
Organism . Short Name: A. thaliana
TAIR Computational Description: ATP binding microtubule motor family protein;(source:Araport11)
TAIR Curator Summary: Encodes a kinesin TETRASPORE. Required for cytokinesis in pollen. In mutants, all four microspore nuclei remain within the same cytoplasm after meiosis.
TAIR Short Description: ATP binding microtubule motor family protein
TAIR Aliases: ATNACK2, NACK2, TES
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Gene
AT1G78790 | locus:2037488 | AT1G78790 | -
Length: 1874  
Chromosome Location: Chr1: 29623205-29625078
Organism . Short Name: A. thaliana
TAIR Computational Description: centromere protein X;(source:Araport11)
TAIR Curator Summary: Encodes a protein with high similarity to mammalian MHF2 that acts in the same pathway as FANCM to restrain class II meiotic crossing over.
TAIR Short Description: NULL
TAIR Aliases: AtMHF2, MHF2
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GO Term
GO:1901962 | S-adenosyl-L-methionine transmembrane transport
Description: The directed movement of S-adenosyl-L-methionine across a membrane.
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Protein Domain
IPR016426
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Gene
AT5G55250 | locus:2161680 | IAMT1 | IAA carboxylmethyltransferase 1
Length: 3548  
Chromosome Location: Chr5: 22407427-22410974
Organism . Short Name: A. thaliana
TAIR Computational Description: IAA carboxylmethyltransferase 1;(source:Araport11)
TAIR Curator Summary: Encodes an enzyme which specifically converts IAA to its methyl ester form MelIAA. This gene belongs to the family of carboxyl methyltransferases whose members catalyze the transfer of the methyl group from S-adenosyl-L-methionine to carboxylic acid-containing substrates to form small molecule methyl esters. Expression of TCP genes is downregulated in mutant iamt1-D. SABATH methyltransferase.
TAIR Short Description: IAA carboxylmethyltransferase 1
TAIR Aliases: AtIAMT1, IAMT1
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Gene
AT4G11640 | locus:2139767 | SR | serine racemase
Length: 1897  
Chromosome Location: Chr4: 7021422-7023318
Organism . Short Name: A. thaliana
TAIR Computational Description: serine racemase;(source:Araport11)
TAIR Curator Summary: Serine racemase, which is a bifunctional PLP-dependent enzyme catalyzing racemization of serine and dehydration of serine to pyruvate in the same way as mammalian serine racemases. similar to mammalian serine racemases.
TAIR Short Description: serine racemase
TAIR Aliases: ATSR, SR
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Gene
AT3G18030 | locus:2087669 | HAL3A | HAL3-like protein A
Length: 1327  
Chromosome Location: Chr3: 6167640-6168966
Organism . Short Name: A. thaliana
TAIR Computational Description: HAL3-like protein A;(source:Araport11)
TAIR Curator Summary: flavin mononucleotide flavoprotein involved in salt and osmotic tolerance HAL3A encodes for phosphopantothenoylcysteine decarboxylase being involved in Coenzyme A biosynthesis. HAL3A is predominant over another gene with the presumably same function (HAL3B).
TAIR Short Description: HAL3-like protein A
TAIR Aliases: ATHAL3, ATHAL3A, HAL3, HAL3A
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Gene
AT3G51040 | locus:2080978 | RTH | RTE1-homolog
Length: 1729  
Chromosome Location: Chr3: 18952073-18953801
Organism . Short Name: A. thaliana
TAIR Computational Description: RTE1-homolog;(source:Araport11)
TAIR Curator Summary: Encodes a protein of 231 amino acids with 51% identity to RTE1 over 209 amino acids. Interacts with RTE1 in planta and appears to function in same pathway to positively regulate ethylene signaling.
TAIR Short Description: RTE1-homolog
TAIR Aliases: RTH
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: CCoAOMT7 for methylation of phenolic compounds forms a methyl donor complex with S-adenosyl-L-homocysteine hydrolase and S-adenosyl-L-methionine synthase
Organism: A. thaliana
Gene: AT4G26220
PubMed Id: 31582217
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: a role for ADK and the S-adenosyl-L-methionine pathway in the control of root gravitropism and cap morphogenesis
Organism: A. thaliana
Gene: ADK1
PubMed Id: 16891550
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Gene
AT3G25820 | locus:2829283 | TPS-CIN | terpene synthase-like sequence-1,8-cineole
Length: 3629  
Chromosome Location: Chr3: 9439146-9442774
Organism . Short Name: A. thaliana
TAIR Computational Description: terpene synthase-like sequence-1,8-cineole;(source:Araport11)
TAIR Curator Summary: Encodes the monoterpene 1,8-cineole synthase, atTPS-Cin. This polypeptide was also shown to synthesize other monoterpenes albeit in minor quantities. The same polypeptide is encoded at two different loci, the result of gene duplication: at3g25820 and at3g25830.
TAIR Short Description: terpene synthase-like sequence-1,8-cineole
TAIR Aliases: ATTPS-CIN, TPS-CIN, TPS23
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Gene
AT3G25830 | locus:2086014 | TPS-CIN | terpene synthase-like sequence-1,8-cineole
Length: 3629  
Chromosome Location: Chr3: 9447409-9451037
Organism . Short Name: A. thaliana
TAIR Computational Description: terpene synthase-like sequence-1,8-cineole;(source:Araport11)
TAIR Curator Summary: Encodes the monoterpene 1,8-cineole synthase, atTPS-Cin. This polypeptide was also shown to synthesize other monoterpenes albeit in minor quantities. The same polypeptide is encoded at two different loci, the result of gene duplication: at3g25820 and at3g25830.
TAIR Short Description: terpene synthase-like sequence-1,8-cineole
TAIR Aliases: ATTPS-CIN, TPS-CIN, TPS27
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Gene
AT3G63540 | locus:5019474795 | AT3G63540 | -
 
Length: 1163  
Chromosome Location: Chr3: 23458642-23459804
Organism . Short Name: A. thaliana
TAIR Computational Description: thylakoid lumenal protein (Mog1/PsbP/DUF1795-like photosystem II reaction center PsbP family protein);(source:Araport11)
TAIR Curator Summary: Conceptual translation of this open reading frame gave the sequence of a 229-residue hypothetical protein that contains the same sequence as the mature A. thaliana chloroplast luminal 19-kDa protein linked to a putative signal sequence. Protein P82658.
TAIR Short Description: Mog1/PsbP/DUF1795-like photosystem II reaction center PsbP family protein
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Publication
25826575
First Author: Lin GM
Title: Mechanistic Investigation of the Radical S-Adenosyl-L-methionine Enzyme DesII Using Fluorinated Analogues.
Year: 2015
Journal: J Am Chem Soc
Volume: 137
Pages: 4964-7
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GO Term
GO:1990543 | mitochondrial S-adenosyl-L-methionine transmembrane transport
Description: The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion.
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GO Term
GO:0000095 | S-adenosyl-L-methionine transmembrane transporter activity
Description: Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
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Gene
AT2G27530 | locus:2042087 | PGY1 | PIGGYBACK1
Length: 1719  
Chromosome Location: Chr2: 11763217-11764935
Organism . Short Name: A. thaliana
TAIR Computational Description: Ribosomal protein L1p/L10e family;(source:Araport11)
TAIR Curator Summary: Encodes ribosomal protein L10aP. Identified in a screen for enhancers of as1. as1/pgy double mutants show defects in leaf vascular patterning and adaxial cell fate. Double mutant analysis indicates pgy genes function in the same pathway as REV, KAN1 and KAN2.
TAIR Short Description: Ribosomal protein L1p/L10e family
TAIR Aliases: PGY1
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Publication
16788729
First Author: Hughes JA
Title: In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose.
Year: 2006
Journal: Can J Microbiol
Volume: 52
Pages: 599-602
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Publication
2199259
First Author: Perham RN
Title: The fructose-1,6-bisphosphate aldolases: same reaction, different enzymes.
Year: 1990
Journal: Biochem Soc Trans
Volume: 18
Pages: 185-7
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Protein Domain
IPR008471
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Gene
AT1G03445 | locus:2825042 | BSU1 | BRI1 SUPPRESSOR 1
Length: 5292  
Chromosome Location: Chr1: 854410-859701
Organism . Short Name: A. thaliana
TAIR Computational Description: Serine/threonine protein phosphatase family protein;(source:Araport11)
TAIR Curator Summary: encodes a serine–threonine protein phosphatase with an N-terminal Kelch-repeat domain, which is nuclear localized and expressed preferentially in elongating cells. Genetic evidence suggest that this gene plays a redundant role (along with other members of the same gene family) in modulating growth in response to brassinosteroid.
TAIR Short Description: Serine/threonine protein phosphatase family protein
TAIR Aliases: BSU1
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Gene
AT1G33140 | locus:2196646 | PGY2 | PIGGYBACK2
Length: 1559  
Chromosome Location: Chr1: 12023225-12024783
Organism . Short Name: A. thaliana
TAIR Computational Description: Ribosomal protein L6 family;(source:Araport11)
TAIR Curator Summary: Encodes ribosomal protein L9. Identified in a screen for enhancers of as1. as1/pgy double mutants show defects in leaf vascular patterning and adaxial cell fate. Double mutant analysis indicates pgy genes function in the same pathway as REV, KAN1 and KAN2. The mRNA is cell-to-cell mobile.
TAIR Short Description: Ribosomal protein L6 family
TAIR Aliases: PGY2
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Protein Domain
IPR002747
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Gene
AT3G01120 | locus:2102072 | MTO1 | METHIONINE OVERACCUMULATION 1
Length: 3401  
Chromosome Location: Chr3: 38759-42159
Organism . Short Name: A. thaliana
TAIR Computational Description: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein;(source:Araport11)
TAIR Curator Summary: encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.
TAIR Short Description: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein
TAIR Aliases: AtCGS1, AtCYS1, CGS, CGS1, MTO1
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Publication
10715319
First Author: Ratcliffe OJ
Title: INTERFASCICULAR FIBERLESS1 is the same gene as REVOLUTA.
Year: 2000
Journal: Plant Cell
Volume: 12
Pages: 315-7
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GO Term
GO:0047625 | adenosylmethionine cyclotransferase activity
Description: Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.
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Gene
AT5G46700 | locus:2178570 | TRN2 | TORNADO 2
Length: 2285  
Chromosome Location: Chr5: 18950843-18953127
Organism . Short Name: A. thaliana
TAIR Computational Description: Tetraspanin family protein;(source:Araport11)
TAIR Curator Summary: Encodes a transmembrane protein of the tetraspanin (TET) family, one of 17 members found in Arabidopsis. Double mutant analysis showed that TRN1 and TRN2 act in the same pathway. Required for the maintenance of both the radial pattern of tissue differentiation in the root and for the subsequent circumferential pattern within the epidermis.
TAIR Short Description: Tetraspanin family protein
TAIR Aliases: TET1, TRN2
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Gene
AT2G19560 | locus:2050414 | EER5 | ENHANCED ETHYLENE RESPONSE 5
Length: 3456  
Chromosome Location: Chr2: 8465690-8469145
Organism . Short Name: A. thaliana
TAIR Computational Description: proteasome family protein;(source:Araport11)
TAIR Curator Summary: encodes a protein with a PAM domain involved in ethylene signaling. eer5 mutants show ethylene hypersensitivity in relation to hypocotyl elongation. EER5 interacts with EIN2 and with COP9 in Y2H assays. EIN3 protein levels are the same in WT and eer5-1 mutants. EER5 may be involved in promoting a dampening of the ethylene response.
TAIR Short Description: proteasome family protein
TAIR Aliases: AtTHP1, EER5, ESSP1, THP1
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Protein Domain
IPR016843
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Gene
AT1G17950 | locus:2030903 | MYB52 | myb domain protein 52
Length: 1809  
Chromosome Location: Chr1: 6177481-6179289
Organism . Short Name: A. thaliana
TAIR Computational Description: myb domain protein 52;(source:Araport11)
TAIR Curator Summary: R2R3-MYB transcription family. Absence of the MYB52 transcription factor is correlated with an increase in PME activity and a decrease in the degree of pectin methylesterification. Transcriptionally activates PECTIN METHYLESTERASE INHIBITOR6 (PMEI6), PMEI14, and SUBTILISIN-LIKE SER PROTEASE1.7 (SBT1.7) by binding to their promoters. MYB52 can bind to the same regulatory regions as the ERF4 transcriptional represssor.
TAIR Short Description: myb domain protein 52
TAIR Aliases: ATMYB52, BW52, MYB52
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Gene
AT4G15880 | locus:2130864 | ESD4 | EARLY IN SHORT DAYS 4
Length: 3628  
Chromosome Location: Chr4: 9012552-9016179
Organism . Short Name: A. thaliana
TAIR Computational Description: Cysteine proteinases superfamily protein;(source:Araport11)
TAIR Curator Summary: EARLY IN SHORT DAYS 4 Arabidopsis mutant shows extreme early flowering and alterations in shoot development. It encodes a SUMO protease, located predominantly at the periphery of the nucleus. Accelerates the transition from vegetative growth to flowering. Probably acts in the same pathway as NUA in affecting flowering time, vegetative and inflorescence development. The mRNA is cell-to-cell mobile.
TAIR Short Description: Cysteine proteinases superfamily protein
TAIR Aliases: ATESD4, ESD4
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Gene
AT3G25520 | locus:2094508 | ATL5 | ribosomal protein L5
Length: 2189  
Chromosome Location: Chr3: 9269277-9271465
Organism . Short Name: A. thaliana
TAIR Computational Description: ribosomal protein L5;(source:Araport11)
TAIR Curator Summary: Encodes ribosomal protein L5 that binds to 5S ribosomal RNA and in involved in its export from the nucleus to the cytoplasm. Identified in a screen for enhancers of as1. as1/pgy double mutants show defects in leaf vascular patterning and adaxial cell fate. Double mutant analysis indicates pgy genes function in the same pathway as REV, KAN1 and KAN2.
TAIR Short Description: ribosomal protein L5
TAIR Aliases: ATL5, OLI5, PGY3, RPL5A
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Gene
AT5G50930 | locus:2157393 | AT5G50930 | -
Length: 2413  
Chromosome Location: Chr5: 20722069-20724481
Organism . Short Name: A. thaliana
TAIR Computational Description: Histone superfamily protein;(source:Araport11)
TAIR Curator Summary: Encodes a protein with similarity to mammalian MHF1 that acts in the same pathway as FANCM to restrain class II meiotic crossing over, and acts with FANCM during meiosis and to repair cross-links. It also assumes an opposing role from FANCM in homologous recombination and only FANCM is essential for replicative repair in the absence of the endonuclease MUS81.
TAIR Short Description: Histone superfamily protein
TAIR Aliases: AtMHF1, MHF1
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Publication
18393394
First Author: Chao KL
Title: The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an alpha/beta-fold characteristic of nucleotide-utilizing enzymes.
Year: 2008
Journal: Proteins
Volume: 72
Pages: 506-9
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Publication
33784078
First Author: Yeh YC
Title: Mechanistic Investigation of 1,2-Diol Dehydration of Paromamine Catalyzed by the Radical S-Adenosyl-l-methionine Enzyme AprD4.
Year: 2021
Journal: J Am Chem Soc
Volume: 143
Pages: 5038-5043
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Publication
25778402
First Author: Nakai T
Title: The Radical S-Adenosyl-L-methionine Enzyme QhpD Catalyzes Sequential Formation of Intra-protein Sulfur-to-Methylene Carbon Thioether Bonds.
Year: 2015
Journal: J Biol Chem
Volume: 290
Pages: 11144-66
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Protein Domain
IPR004159
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Gene
AT5G66190 | locus:2156917 | FNR1 | ferredoxin-NADP( )-oxidoreductase 1
Length: 2236  
Chromosome Location: Chr5: 26450964-26453199
Organism . Short Name: A. thaliana
TAIR Computational Description: ferredoxin-NADP[+]-oxidoreductase 1;(source:Araport11)
TAIR Curator Summary: Encodes a leaf-type ferredoxin:NADP(H) oxidoreductase. It is present in both chloroplast stroma and thylakoid membranes but is more abundant in the thylakoid. The affinity of this enzyme for ferredoxin is slightly, but significantly, higher than AtLFNR2, an isoform of the same enzyme. AtLFNR1 forms a heterodimer with AtFNR2 and is also a prerequisite to attach AtFNR2 to the thylakoid membrane.
TAIR Short Description: ferredoxin-NADP(+)-oxidoreductase 1
TAIR Aliases: ATLFNR1, FNR1, LFNR1
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Protein Domain
IPR022923
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Protein
1A111_ARATH | Q9S9U6
Organism . Name: Arabidopsis thaliana
Length: 460  
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Publication
12934018
First Author: Chiba Y
Title: S-adenosyl-L-methionine is an effector in the posttranscriptional autoregulation of the cystathionine gamma-synthase gene in Arabidopsis.
Year: 2003
Journal: Proc Natl Acad Sci U S A
Volume: 100
Pages: 10225-30
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Gene
AT4G21610 | locus:2119622 | LOL2 | lsd one like 2
Length: 1448  
Chromosome Location: Chr4: 11488976-11490423
Organism . Short Name: A. thaliana
TAIR Computational Description: lsd one like 2;(source:Araport11)
TAIR Curator Summary: Contains the same novel zinc finger motif with LSD1, a negative regulator of cell death and defense response. Due to differential splicing, it encodes two different proteins, one of which contains an additional, putative DNA binding motif. Northern analysis demonstrated that LOL2 transcripts containing the additional DNA binding motif are predominantly upregulated after treatment with both virulent and avirulent Pseudomonas syringae pv maculicola strains.
TAIR Short Description: lsd one like 2
TAIR Aliases: LOL2
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Gene
AT5G16510 | locus:2171362 | RGP5 | reversibly glycosylated polypeptide 5
Length: 1998  
Chromosome Location: Chr5: 5392576-5394573
Organism . Short Name: A. thaliana
TAIR Computational Description: Alpha-1,4-glucan-protein synthase family protein;(source:Araport11)
TAIR Curator Summary: RGP5 is a member of the reversably-glycosylated family of proteins. Analyses using tagged RGP5 suggest that it is present in the cytosol and in association with the Golgi apparatus. Recombinant RGP5 does not have UDP-arabinose mutase activity based on an in vitro assay even though the related RGP1, RGP2, and RGP3 proteins do have activity in the same assay. RGP5 can form complexes with RGP1 and RGP2.
TAIR Short Description: Alpha-1,4-glucan-protein synthase family protein
TAIR Aliases: RGP5
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GeneRIF (Gene Reference into Function)
GeneRIF (Gene Reference into Function)
Annotation: These results show that S-adenosyl-L-methionine induces the stacking of ribosomes on CGS1 mRNA and that multiple mRNA degradation sites probably correspond to each stacked ribosome.
Organism: A. thaliana
Gene: MTO1
PubMed Id: 18184691
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Gene
AT4G32410 | locus:2127776 | CESA1 | cellulose synthase 1
Length: 6355  
Chromosome Location: Chr4: 15640490-15646844
Organism . Short Name: A. thaliana
TAIR Computational Description: cellulose synthase 1;(source:Araport11)
TAIR Curator Summary: Encodes a cellulose synthase isomer. CESA1 mutants have cellulose defect in the primary cell wall. Multiple lines of evidence suggest that CESA1, along with CESA3 and CESA6 are present in the same plasma membrane complex for cellulose biosynthesis. lasma membrane complex for cellulose biosynthesis. As inferred from the null role of secondary wall-type CesAs, included in a set of five primary wall-type CesAs that may support trichome cell wall thickening.
TAIR Short Description: cellulose synthase 1
TAIR Aliases: ANY1, AtCESA1, CESA1, RSW1
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Gene
AT1G79280 | locus:2207390 | NUA | nuclear pore anchor
Length: 14047  
Chromosome Location: Chr1: 29818970-29833016
Organism . Short Name: A. thaliana
TAIR Computational Description: nuclear pore anchor;(source:Araport11)
TAIR Curator Summary: Encodes a 237-kDA protein with similarity to vertebrate Tpr, a long coiled-coil proteins of nuclear pore inner basket filaments. It is localized to the inner surface of the nuclear envelope and is a component of the nuclear pore-associated steps of sumoylation and mRNA export in plants. Mutations affect flowering time regulation and other developmental processes. Probably acts in the same pathway as ESD4 in affecting flowering time, vegetative and inflorescence development.
TAIR Short Description: nuclear pore anchor
TAIR Aliases: AtTPR, NUA
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Gene
AT4G11260 | locus:2128278 | SGT1B | -
Length: 2729  
Chromosome Location: Chr4: 6851184-6853912
Organism . Short Name: A. thaliana
TAIR Computational Description: phosphatase-like protein;(source:Araport11)
TAIR Curator Summary: Functions in plant disease resistance signaling, SCF(TIR1) mediated degradation of Aux/IAA proteins and HSP90 mediated degradation of R resistance proteins. AtSGT1a and AtSGT1b are functionally redundant in the resistance to pathogenes. AtSGT1b was more highly expressed than AtSGT1. The N-terminal TPR domain of AtSGT1a reduces the steady-state level of Arabidopsis SGT1 proteins whereas the same domain from AtSGT1b enhances SGT1 accumulation. The TPR domain is dispensable for SGT1 resistance.
TAIR Short Description: phosphatase-related
TAIR Aliases: ATSGT1B, EDM1, ETA3, RPR1, SGT1B
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Gene
AT5G50750 | locus:2163305 | RGP4 | reversibly glycosylated polypeptide 4
Length: 1796  
Chromosome Location: Chr5: 20640992-20642787
Organism . Short Name: A. thaliana
TAIR Computational Description: reversibly glycosylated polypeptide 4;(source:Araport11)
TAIR Curator Summary: RGP4 is a reversibly glycosylated polypeptide. Analyses using tagged RGP4 suggest that it is present in the cytosol and in association with the Golgi apparatus. Recombinant RGP4 does not have UDP-arabinose mutase activity based on an in vitro assay even though the related RGP1, RGP2, and RGP3 proteins do have activity in the same assay. RGP4 can form complexes with RGP1 and RGP2. RGP4 is expressed during seed development.
TAIR Short Description: reversibly glycosylated polypeptide 4
TAIR Aliases: RGP4
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Protein Domain
IPR017031
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GO Term
GO:0043621 | protein self-association
Description: Binding to a domain within the same polypeptide.
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Publication
19746907
First Author: Szu PH
Title: Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.
Year: 2009
Journal: J Am Chem Soc
Volume: 131
Pages: 14030-42
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Publication
27158836
First Author: Bruender NA
Title: The Radical S-Adenosyl-l-methionine Enzyme MftC Catalyzes an Oxidative Decarboxylation of the C-Terminus of the MftA Peptide.
Year: 2016
Journal: Biochemistry
Volume: 55
Pages: 2813-6
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Publication
23874663
First Author: Feng J
Title: Discovery and characterization of BlsE, a radical S-adenosyl-L-methionine decarboxylase involved in the blasticidin S biosynthetic pathway.
Year: 2013
Journal: PLoS One
Volume: 8
Pages: e68545
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Gene
AT4G23570 | locus:2128404 | SGT1A | -
Length: 3187  
Chromosome Location: Chr4: 12299749-12302935
Organism . Short Name: A. thaliana
TAIR Computational Description: phosphatase-like protein;(source:Araport11)
TAIR Curator Summary: Closely related to SGT1B, may function in SCF(TIR1) mediated protein degradation. AtSGT1a and AtSGT1b are functionally redundant in the resistance to pathogenes. AtSGT1b was more highly expressed than AtSGT1. The N-terminal TPR domain of AtSGT1a reduces the steady-state level of Arabidopsis SGT1 proteins whereas the same domain from AtSGT1b enhances SGT1 accumulation. The TPR domain is dispensable for SGT1 resistance. AtSGT1a is induced upon pathogen infection and can function in R gene-mediated resistance.
TAIR Short Description: phosphatase-related
TAIR Aliases: SGT1A
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Protein Domain
IPR017342
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Protein Domain
IPR016853
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Protein Domain
IPR024160
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Protein Domain
IPR012511
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Gene
AT5G05170 | locus:2156789 | CEV1 | CONSTITUTIVE EXPRESSION OF VSP 1
Length: 5427  
Chromosome Location: Chr5: 1530132-1535558
Organism . Short Name: A. thaliana
TAIR Computational Description: Cellulose synthase family protein;(source:Araport11)
TAIR Curator Summary: Encodes a cellulose synthase isomer. CESA3 mutants have cellulose defect in the primary cell wall. Multiple lines of evidence suggest that CESA3, along with CESA1 and CESA6 are present in the same plasma membrane complex for cellulose biosynthesis. As inferred from the null role of secondary wall-type CesAs, included in a set of five primary wall-type CesAs that may support trichome cell wall thickening. The xylem cells in primary root have reduced cell expansion and higher than normal lignification.
TAIR Short Description: Cellulose synthase family protein
TAIR Aliases: ATCESA3, ATH-B, CESA3, CEV1, ELI1, IXR1, MRE1
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Protein Domain
IPR016980
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Protein Domain
IPR005911
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Interaction Term
MI:0516 | methyltransferase radiometric assay
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Publication
19716619
First Author: Hennig L
Title: Diversity of Polycomb group complexes in plants: same rules, different players?
Year: 2009
Journal: Trends Genet
Volume: 25
Pages: 414-23
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Publication
21205613
First Author: Timm S
Title: The hydroxypyruvate-reducing system in Arabidopsis: multiple enzymes for the same end.
Year: 2011
Journal: Plant Physiol
Volume: 155
Pages: 694-705
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Publication
8672889
First Author: Mireau H
Title: The same Arabidopsis gene encodes both cytosolic and mitochondrial alanyl-tRNA synthetases.
Year: 1996
Journal: Plant Cell
Volume: 8
Pages: 1027-39
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Gene
AT5G64740 | locus:2176090 | CESA6 | cellulose synthase 6
Length: 5696  
Chromosome Location: Chr5: 25881033-25886728
Organism . Short Name: A. thaliana
TAIR Computational Description: cellulose synthase 6;(source:Araport11)
TAIR Curator Summary: Encodes a cellulose synthase isomer. CESA6 mutants have cellulose defect in the primary cell wall. Multiple lines of evidence suggest that CESA6, along with CESA1 and CESA3 are present in the same plasma membrane complex for cellulose biosynthesis. CESA2 and CESA5 are related to CESA6, having partially redundant roles. As inferred from the null role of secondary wall-type CesAs, included in a set of five primary wall-type CesAs that may support trichome cell wall thickening. The mRNA is cell-to-cell mobile.
TAIR Short Description: cellulose synthase 6
TAIR Aliases: CESA6, E112, IXR2, PRC1
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GO Term
GO:0032840 | intramolecular proline-rich ligand binding
Description: Binding to a proline-rich region within the same polypeptide.
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Publication
11844113
First Author: Shen B
Title: High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene.
Year: 2002
Journal: Plant J
Volume: 29
Pages: 371-80
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Protein
1A17_ARATH | Q9STR4
Organism . Name: Arabidopsis thaliana
Length: 447  
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Protein
1A18_ARATH | Q9T065
Organism . Name: Arabidopsis thaliana
Length: 469  
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Gene
AT5G66690 | locus:2173664 | UGT72E2 | -
Length: 1774  
Chromosome Location: Chr5: 26625049-26626822
Organism . Short Name: A. thaliana
TAIR Computational Description: UDP-Glycosyltransferase superfamily protein;(source:Araport11)
TAIR Curator Summary: UGT72E2 is an UDPG:coniferyl alcohol glucosyltransferase which glucosylates sinapyl- and coniferyl aldehydes as well as sinapyl- and coniferyl alcohol. The enzyme is thought to be involved in lignin metabolism. A knockdown mutant line (72E2KD) was obtained using RNAi silencing. A twofold reduction in coniferyl alcohol 4-O-glucoside and sinapyl alcohol 4-O-glucoside was detected in this line compared to wildtype. In comparison, both knockout and knockdown lines of UGT72E1 and UGT72E3, respectively, failed to display the same reduction in phenylpropanoid 4-O-glucosides. The mRNA is cell-to-cell mobile.
TAIR Short Description: UDP-Glycosyltransferase superfamily protein
TAIR Aliases: UGT72E2
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GO Term
GO:0035425 | autocrine signaling
Description: Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.
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Gene
AT5G55540 | locus:2173952 | TRN1 | TORNADO 1
Length: 4519  
Chromosome Location: Chr5: 22496196-22500714
Organism . Short Name: A. thaliana
TAIR Computational Description: tornado 1;(source:Araport11)
TAIR Curator Summary: Encodes a large plant-specific protein of unknown function, with conserved domains also found in a variety of signaling proteins, In trn mutants, the leaf venation network had a severely reduced complexity: incomplete loops, no tertiary or quaternary veins, and vascular islands. The leaf laminas were asymmetric and narrow because of a severely reduced cell number. TRN1 is required for the maintenance of both the radial pattern of tissue differentiation in the root and for the subsequent circumferential pattern within the epidermis. Double mutant analysis showed that TRN1 and TRN2 act in the same pathway.
TAIR Short Description: tornado 1
TAIR Aliases: LOP1, TRN1
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Publication
12626710
First Author: Gojkovic Z
Title: Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties.
Year: 2003
Journal: Nucleic Acids Res
Volume: 31
Pages: 1683-92
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Publication
21737279
First Author: Arnaud N
Title: The same regulatory point mutation changed seed-dispersal structures in evolution and domestication.
Year: 2011
Journal: Curr Biol
Volume: 21
Pages: 1215-9
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Publication
15503145
First Author: Vicari D
Title: Virulence regulators RfaH and YaeQ do not operate in the same pathway.
Year: 2004
Journal: Mol Genet Genomics
Volume: 272
Pages: 489-96
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Publication
23882017
 
First Author: Ruhe ZC
Title: Receptor polymorphism restricts contact-dependent growth inhibition to members of the same species.
Year: 2013
Journal: mBio
Volume: 4
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Publication
27007615
First Author: Bruender NA
Title: Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-L-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link.
Year: 2016
Journal: Biochemistry
Volume: 55
Pages: 2122-34
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Gene
AT5G55910 | locus:2178388 | D6PK | D6 protein kinase
Length: 2602  
Chromosome Location: Chr5: 22639813-22642414
Organism . Short Name: A. thaliana
TAIR Computational Description: D6 protein kinase;(source:Araport11)
TAIR Curator Summary: Member of AGC VIIIa Kinase family. D6PK is a protein kinase involved that plays a role in polar auxin transport. Most likely acts redundantly with the related proteins: D6PKL1,D6PKL2,and D6PKL3. PIN1 is a target of D6PK phosphorylation. D6PK is associated with sterol enriched membrane rafts and may be involved in regulation of the switch from basal to planar polarity during root hair initiation. Involved in pulse-induced phototropism but also for time-dependent second positive phototropism. Works with PIN3 in the same genetic pathway of hypocotyl phototropism under all light conditions. Involved in the generation of auxin asymmetrical distribution induced by phototropic stimulation.
TAIR Short Description: D6 protein kinase
TAIR Aliases: AGC1-1, D6PK
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Gene
AT2G25010 | locus:2047339 | AT2G25010 | -
Length: 2224  
Chromosome Location: Chr2: 10631531-10633754
Organism . Short Name: A. thaliana
TAIR Computational Description: Aminotransferase-like, plant mobile domain family protein;(source:Araport11)
TAIR Curator Summary: Encodes a nuclear localized aminotransferase like protein containing a plant mobile domain. MAIL1 is expressed in the root, SAM, leaves, flowers and embryo. Loss of function mutations display defects in root and shoot growth. In the root, primary root growth terminates early. In the shoot, leaf development is delayed, and lateral organs are smaller than normal. MAIL1 appears to affect meristem cell division and cell fate. Biochemical analysis of the mutants also demonstrates silencing defects. Based on epistasis analysis, this MAIN1 acts in a different pathway than DNA methylation, and siRNA and in the same pathway as MAIL1 and PP7L.
TAIR Short Description: Aminotransferase-like, plant mobile domain family protein
TAIR Aliases: MAIL1
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Gene
AT2G13540 | locus:2054137 | ABH1 | ABA HYPERSENSITIVE 1
Length: 6183  
Chromosome Location: Chr2: 5636884-5643066
Organism . Short Name: A. thaliana
TAIR Computational Description: ARM repeat superfamily protein;(source:Araport11)
TAIR Curator Summary: Encodes a nuclear cap-binding protein that forms a heterodimeric complex with CBP20 and is involved in ABA signaling and flowering. Mutants are early flowering and exhibit hypersensitive response to ABA in germination inhibition.Loss of ABH1 function results in abnormal processing of mRNAs for several important floral regulators (FLC, CO, FLM). Analysis of loss of function mutations suggests a role in pri-miRNA processing and mRNA splicing. Note that two different mutant alleles were given the same name abh1-7 (Kuhn et al 2007; Kim et al 2008). To avoid confusion, abh1-7 described in Kim et al (2008) has been renamed abh1-107 (other names: ensalada-1, ens-1).
TAIR Short Description: ARM repeat superfamily protein
TAIR Aliases: ABH1, ATCBP80, CBP80, ENS
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Gene
AT5G50700 | locus:2832487 | HSD1 | hydroxysteroid dehydrogenase 1
Length: 2256  
Chromosome Location: Chr5: 20623024-20625279
Organism . Short Name: A. thaliana
TAIR Computational Description: hydroxysteroid dehydrogenase 1;(source:Araport11)
TAIR Curator Summary: Encodes a hydroxysteroid dehydrogenase HSD1. Two copies of HSD1 (At5g50600 and At5g50700) exist in the Arabidopsis genome as a result of an exact 33-kb duplication on chromosome 5 encompassing seven genes. There are five homologs of HSD1 in Arabidopsis (HSD2-At3g47350, HSD3-At3g47360, HSD4-At5g50590, HSD4-At5g50690 and HSD6-At5g50770; HSD4 has two copies due to the same gene duplication event occurred to HSD1) (Plant Cell Physiology 50:1463). At5g50690 is also named as HSD7 (Plant Physiology 145:87). HSD1 is identified from the proteome of oil bodies from mature seeds. Transcription of HSD1 is specifically and highly induced in oil-accumulating tissues of mature seeds; transcript disappears during germination.
TAIR Short Description: hydroxysteroid dehydrogenase 1
TAIR Aliases: HSD1
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Protein Domain
IPR010940
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GO Term
GO:0032432 | actin filament bundle
Description: An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
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Gene
AT5G15410 | locus:2180867 | DND1 | DEFENSE NO DEATH 1
Length: 3657  
Chromosome Location: Chr5: 5003226-5006882
Organism . Short Name: A. thaliana
TAIR Computational Description: Cyclic nucleotide-regulated ion channel family protein;(source:Araport11)
TAIR Curator Summary: 'defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2 (article ID 229): Cyclic nucleotide gated channel, activated by cAMP, conducts K+ and other monovalent cations but excludes Na+, does not contain the GYG amino acid sequence found in other channels with this conductivity profile. Conducts Ca2+ into cells which is linked to the generation of NO and the NO signaling pathway involved in the innate immune response to pathogens. CNGC2 could be the key step mediating bulk Ca2+ influx into leaf cells after unloading from the vascular and have no direct roles in the leaf development and HR.
TAIR Short Description: Cyclic nucleotide-regulated ion channel family protein
TAIR Aliases: ATCNGC2, CNGC2, DND1
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Interaction Experiment
Interaction Experiment
Name: Serino G (1999)
Description: Arabidopsis cop8 and fus4 mutations define the same gene that encodes subunit 4 of the COP9 signalosome.
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Publication
10648622
First Author: Pintard L
Title: Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.
Year: 2000
Journal: Mol Cell Biol
Volume: 20
Pages: 1370-81
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Protein
1A14_ARATH | Q43309
Organism . Name: Arabidopsis thaliana
Length: 474  
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