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Search results 1 to 100 out of 682 for Differentially alternatively spliced

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Type Details Score
SO Term
Description: An attribute describing a situation where a gene may encode for more than 1 transcript.
Ontology Term Synonym
Name: alternatively spliced
Type: synonym
SO Term
Description: A transcript that is alternatively spliced.
Ontology Term Synonym
Name: alternatively spliced transcript
Type: synonym
Gene
Length: 5097  
Chromosome Location: Chr3: 6336692-6341788
Organism . Short Name: A. thaliana
TAIR Computational Description: CCAAT-displacement protein alternatively spliced product;(source:Araport11)
TAIR Curator Summary: This gene is predicted to encode a protein that functions as a Golgi apparatus structural component, known as a golgin in mammals and yeast. A fluorescently-tagged version of CASP co-localizes with Golgi markers, and this localization appears to require the C-terminal (565–689aa) portion of the protein. The protein is inserted into a membrane in a type II orientation.
TAIR Short Description: CCAAT-displacement protein alternatively spliced product
TAIR Aliases: AtCASP, CASP
Publication
First Author: Payne JA
Title: Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney.
Year: 1994
Journal: Proc Natl Acad Sci U S A
Volume: 91
Pages: 4544-8
Publication
First Author: Lamers MB
Title: Human MAFA has alternatively spliced variants.
Year: 1998
Journal: Biochim Biophys Acta
Volume: 1399
Pages: 209-12
Gene
Length: 3706  
Chromosome Location: Chr1: 24468770-24472475
Organism . Short Name: A. thaliana
TAIR Computational Description: receptor kinase 1;(source:Araport11)
TAIR Curator Summary: An alternatively spliced gene that encodes a functional transmembrane receptor serine/threonine kinase, alternate form may not have transmembrane domain.
TAIR Short Description: receptor kinase 1
TAIR Aliases: ARK1, RK1, SDK1
Publication
First Author: Faulkner G
Title: ZASP: a new Z-band alternatively spliced PDZ-motif protein.
Year: 1999
Journal: J Cell Biol
Volume: 146
Pages: 465-75
Publication
First Author: Asselin-Mullen P
Title: Protein interaction network of alternatively spliced NudCD1 isoforms.
Year: 2017
Journal: Sci Rep
Volume: 7
Pages: 12987
GeneRIF (Gene Reference into Function)
Annotation: The two alternatively spliced isoforms of SR$% have distinct biological functions.
Organism: A. thaliana
Gene: SR45
PubMed Id: 19403727
Publication
First Author: Ciccarelli FD
Title: AMOP, a protein module alternatively spliced in cancer cells.
Year: 2002
Journal: Trends Biochem Sci
Volume: 27
Pages: 113-5
Publication
First Author: Papp LV
Title: Functional characterization of alternatively spliced human SECISBP2 transcript variants.
Year: 2008
Journal: Nucleic Acids Res
Volume: 36
Pages: 7192-206
Gene
Length: 2346  
Chromosome Location: Chr3: 22900050-22902395
Organism . Short Name: A. thaliana
TAIR Computational Description: RNA-binding (RRM/RBD/RNP motifs) family protein;(source:Araport11)
TAIR Curator Summary: encodes an arginine/serine-rich splicing factor. transcript is alternatively spliced and is differentially expressed in different tissues (flowers, roots, stems, and leaves) examined. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
TAIR Short Description: RNA-binding (RRM/RBD/RNP motifs) family protein
TAIR Aliases: At-RS31, ATRSP31, RS31, RSP31
Publication
First Author: Hartmann L
Title: Subcellular Compartmentation of Alternatively Spliced Transcripts Defines SERINE/ARGININE-RICH PROTEIN30 Expression.
Year: 2018
Journal: Plant Physiol
Volume: 176
Pages: 2886-2903
Gene
Length: 4792  
Chromosome Location: Chr5: 3359832-3364623
Organism . Short Name: A. thaliana
TAIR Computational Description: Translation elongation factor EF1A/initiation factor IF2gamma family protein;(source:Araport11)
TAIR Curator Summary: Transcripts of this gene are alternatively spliced to encode either HBS1, a decoding factor translational GTPase, or SKI7, a component of the cytosolic RNA exosome.
TAIR Short Description: Translation elongation factor EF1A/initiation factor IF2gamma family protein
TAIR Aliases: HBS1, SKI7
GeneRIF (Gene Reference into Function)
Annotation: AT4G24900 encoding a C2H2-domain protein with alternatively spliced transcripts is essential for endosperm development.
Organism: A. thaliana
Gene: TTL
PubMed Id: 22991160
Publication
First Author: Putilina T
Title: Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain.
Year: 1998
Journal: Biochem Biophys Res Commun
Volume: 252
Pages: 433-9
Publication
First Author: Salzman GS
Title: Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.
Year: 2016
Journal: Neuron
Volume: 91
Pages: 1292-1304
Publication
First Author: Saulière J
Title: The exon junction complex differentially marks spliced junctions.
Year: 2010
Journal: Nat Struct Mol Biol
Volume: 17
Pages: 1269-71
mRNA
Length: 2494  
Chromosome Location: Chr3: 6336692-6341788
Publication    
First Author: Filichkin SA
Title: Environmental Stresses Modulate Abundance and Timing of Alternatively Spliced Circadian Transcripts in Arabidopsis.
Year: 2014
Journal: Mol Plant
Publication
First Author: Angiolillo A
Title: The human homologue of the mouse Surf5 gene encodes multiple alternatively spliced transcripts.
Year: 2002
Journal: Gene
Volume: 284
Pages: 169-78
Gene
Length: 1342  
Chromosome Location: Chr5: 20451228-20452569
Organism . Short Name: A. thaliana
TAIR Computational Description: protein-l-isoaspartate methyltransferase 2;(source:Araport11)
TAIR Curator Summary: L-isoaspartyl methyltransferase 2 (PIMT2)gene, alternatively spliced.
TAIR Short Description: protein-l-isoaspartate methyltransferase 2
TAIR Aliases: AtPIMT2, PIMT2
Protein Domain
Publication
First Author: Burgess RW
Title: Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction.
Year: 1999
Journal: Neuron
Volume: 23
Pages: 33-44
Publication
First Author: Lee NS
Title: Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness.
Year: 2015
Journal: Sci Rep
Volume: 5
Pages: 11207
Publication
First Author: Leyland ML
Title: An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1.
Year: 2004
Journal: J Biol Chem
Volume: 279
Pages: 43427-36
Publication
First Author: Zhang XN
Title: Two alternatively spliced isoforms of the Arabidopsis SR45 protein have distinct roles during normal plant development.
Year: 2009
Journal: Plant Physiol
Volume: 150
Pages: 1450-8
Publication
First Author: Lu X
Title: An Arabidopsis gene encoding a C2H2-domain protein with alternatively spliced transcripts is essential for endosperm development.
Year: 2012
Journal: J Exp Bot
Volume: 63
Pages: 5935-44
Gene
Length: 3390  
Chromosome Location: Chr5: 21130320-21133709
Organism . Short Name: A. thaliana
TAIR Computational Description: RNA-binding (RRM/RBD/RNP motifs) family protein;(source:Araport11)
TAIR Curator Summary: Encodes an arginine/serine-rich splicing factor. Transcript is alternatively spliced and is differentially expressed in different tissues (flowers, roots, stems, and leaves) examined. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926. RS41 binds to HYL1 and co-localizes to the nuclear dicing body. Along with RS41, it appears to be involved in pri-miRNA processing and miRNA biogenesis.
TAIR Short Description: RNA-binding (RRM/RBD/RNP motifs) family protein
TAIR Aliases: At-RS41, ATRSP41, RS41
Publication
First Author: Appukuttan B
Title: Identification of novel alternatively spliced isoforms of RTEF-1 within human ocular vascular endothelial cells and murine retina.
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Volume: 48
Pages: 3775-82
Protein Domain
Protein Domain
GeneRIF (Gene Reference into Function)
Annotation: the first low-affinity Mg(2+) transporter from a higher plant encoded by a gene with alternatively spliced transcripts that produce proteins with distinct functions
Organism: A. thaliana
Gene: MGT7
PubMed Id: 19093971
Gene
Length: 2987  
Chromosome Location: Chr4: 13024498-13027484
Organism . Short Name: A. thaliana
TAIR Computational Description: arginine/serine-rich splicing factor 35;(source:Araport11)
TAIR Curator Summary: Encodes an arginine/serine-rich splicing factor. The transcript is alternatively spliced and is differentially expressed in different tissues (flowers, roots, stems, and leaves) examined. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926. RS40 binds to HYL1 and co-localizes to the nuclear dicing body. Along with RS41, it appears to be involved in pri-miRNA processing and miRNA biogenesis (DOI:10.1093/nar/gkv751).
TAIR Short Description: arginine/serine-rich splicing factor 35
TAIR Aliases: At-RS40, AT-SRP40, ATRSP35, ATRSP40, RS40, RSP35
Publication
First Author: Varkonyi-Gasic E
Title: Kiwifruit floral gene APETALA2 is alternatively spliced and accumulates in aberrant indeterminate flowers in the absence of miR172.
Year: 2012
Journal: Plant Mol Biol
Volume: 78
Pages: 417-29
Publication
First Author: Mimida N
Title: Two alternatively spliced transcripts generated from OsMUS81, a rice homolog of yeast MUS81, are up-regulated by DNA-damaging treatments.
Year: 2007
Journal: Plant Cell Physiol
Volume: 48
Pages: 648-54
Publication
First Author: Erdmann KS
Title: The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain.
Year: 2000
Journal: Oncogene
Volume: 19
Pages: 3894-901
Publication
First Author: Hovhannisyan RH
Title: Heterogeneous ribonucleoprotein m is a splicing regulatory protein that can enhance or silence splicing of alternatively spliced exons.
Year: 2007
Journal: J Biol Chem
Volume: 282
Pages: 36265-74
Protein Domain
Gene
Length: 3848  
Chromosome Location: Chr1: 2932739-2936586
Organism . Short Name: A. thaliana
TAIR Computational Description: respiratory burst oxidase-like protein;(source:Araport11)
TAIR Curator Summary: NADPH-oxidase AtrbohB plays a role in seed after-ripening. Major producer of superoxide in germinating seeds. AtrbohB pre-mRNA is alternatively spliced in seeds in a hormonally and developmentally regulated manner. ABA caused accumulation of AtrbohB-ß mRNA and prevented prevented AtrbohB-a mRNA expression in fresh seeds.
TAIR Short Description: respiratory burst oxidase homolog B
TAIR Aliases: ATRBOHB, ATRBOHB-BETA, RBOHB
Publication
First Author: Tanabe N
Title: Differential expression of alternatively spliced mRNAs of Arabidopsis SR protein homologs, atSR30 and atSR45a, in response to environmental stress.
Year: 2007
Journal: Plant Cell Physiol
Volume: 48
Pages: 1036-49
Publication
First Author: Raya A
Title: Goodpasture antigen-binding protein, the kinase that phosphorylates the goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis.
Year: 2000
Journal: J Biol Chem
Volume: 275
Pages: 40392-9
Publication
First Author: Ragone G
Title: The Drosophila melanogaster gene for the NADH:ubiquinone oxidoreductase acyl carrier protein: developmental expression analysis and evidence for alternatively spliced forms.
Year: 1999
Journal: Mol Gen Genet
Volume: 261
Pages: 690-7
Publication
First Author: Kanno T
Title: Identification of Coilin Mutants in a Screen for Enhanced Expression of an Alternatively Spliced GFP Reporter Gene in Arabidopsis thaliana.
Year: 2016
Journal: Genetics
Volume: 203
Pages: 1709-20
Publication
First Author: Gupta S
Title: Two novel arginine/serine (SR) proteins in maize are differentially spliced and utilize non-canonical splice sites.
Year: 2005
Journal: Biochim Biophys Acta
Volume: 1728
Pages: 105-14
Protein Domain
GeneRIF (Gene Reference into Function)
Annotation: The alternatively spliced 5' domain of NDC1 strongly influences the expression of the functionally unrelated ACTIN2, which is a common reference gene in Arabidopsis thaliana for quantitative RT-PCR.
Organism: A. thaliana
Gene: ACT2
PubMed Id: 22195593
GeneRIF (Gene Reference into Function)
Annotation: The alternatively spliced 5' domain of NDC1 strongly influences the expression of the functionally unrelated ACTIN2, which is a common reference gene in Arabidopsis thaliana for quantitative RT-PCR.
Organism: A. thaliana
Gene: NDC1
PubMed Id: 22195593
Publication
First Author: Zhang J
Title: The FLOWERING LOCUS T orthologous gene of Platanus acerifolia is expressed as alternatively spliced forms with distinct spatial and temporal patterns.
Year: 2011
Journal: Plant Biol (Stuttg)
Volume: 13
Pages: 809-20
Protein Domain
Publication
First Author: Wallström SV
Title: An alternatively spliced domain of the NDC1 NAD(P)H dehydrogenase gene strongly influences the expression of the ACTIN2 reference gene in Arabidopsis thaliana.
Year: 2012
Journal: Plant Sci
Volume: 183
Pages: 190-6
Publication
First Author: Gillingham AK
Title: CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin.
Year: 2002
Journal: Mol Biol Cell
Volume: 13
Pages: 3761-74
Gene
Length: 3439  
Chromosome Location: Chr1: 2942538-2945976
Organism . Short Name: A. thaliana
TAIR Computational Description: SERINE-ARGININE PROTEIN 30;(source:Araport11)
TAIR Curator Summary: Encodes a serine-arginine rich RNA binding protein involved in regulation of splicing (including splicing of itself). Exists as 3 alternative spliced forms that are differentially expressed. AT1G09140.1 predominantly accumulates in the cytosol in light grown plants.Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
TAIR Short Description: SERINE-ARGININE PROTEIN 30
TAIR Aliases: At-SR30, ATSRP30, SR30
Gene
Length: 2118  
Chromosome Location: Chr2: 8418078-8420195
Organism . Short Name: A. thaliana
TAIR Computational Description: O-Glycosyl hydrolases family 17 protein;(source:Araport11)
TAIR Curator Summary: Homolog of ZET, an atypical β-1,3 glucanase. Differentially expressed in Ler (very low) vs Col (very high) backgrounds.
TAIR Short Description: O-Glycosyl hydrolases family 17 protein
TAIR Aliases: ZETH
Protein Domain
Publication
First Author: Habuchi H
Title: Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties.
Year: 2003
Journal: Biochem J
Volume: 371
Pages: 131-42
SO Term
Description: An intron that spliced via endonucleolytic cleavage and ligation rather than transesterification.
Ontology Term Synonym
Name: spliced leader RNA
Type: synonym
Ontology Term Synonym
Name: autocatalytically spliced intron
Type: synonym
Ontology Term Synonym
Name: trans spliced transcript
Type: synonym
Ontology Term Synonym
Name: endonuclease spliced intron
Type: synonym
GeneRIF (Gene Reference into Function)
Annotation: Data show that in mutants impaired in the nonsense-mediated decay (NMD) components UPF1, levels of the alternatively spliced AtGRP7 and AtGRP8 transcripts are strongly elevated, implicating UPF1 in the decay of these clock-regulated transcripts.
Organism: A. thaliana
Gene: LBA1
PubMed Id: 17924945
GeneRIF (Gene Reference into Function)
Annotation: Data show that in mutants impaired in the nonsense-mediated decay (NMD) components UPF3, levels of the alternatively spliced AtGRP7 and AtGRP8 transcripts are strongly elevated, implicating UPF3 in the decay of these clock-regulated transcripts.
Organism: A. thaliana
Gene: UPF3
PubMed Id: 17924945
GeneRIF (Gene Reference into Function)
Annotation: Data show that AtGRP8 binds to AtGRP7 and levels of the alternatively spliced AtGRP8 transcripts that contain premature termination codons are strongly elevated in mutants impaired in the nonsense-mediated decay (NMD) components UPF1 or UPF3.
Organism: A. thaliana
Gene: CCR1
PubMed Id: 17924945
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Protein Domain
Publication
First Author: Hu B
Title: The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative.
Year: 2001
Journal: Biochem Biophys Res Commun
Volume: 285
Pages: 1369-76
Protein Domain
GeneRIF (Gene Reference into Function)
Annotation: A subset of alternatively spliced transcripts and 5'-extended mRNAs with Nonsense-mediated decay (NMD)-eliciting features accumulated in the fry2-1 mutant, cycloheximide-treated wild type, and upf3 mutant plants, indicating that FRY2 is essential for the degradation of these NMD transcripts.
Organism: A. thaliana
Gene: CPL1
PubMed Id: 26887918
SO Term
Description: A gene that encodes more than one transcript.
SO Term
Description: Snall nuclear RNAs that are incorporated into the pre-mRNAs to replace the 5' end in some eukaryotes.
Ontology Term Synonym
Name: encodes alternately spliced transcripts
Type: synonym
GeneRIF (Gene Reference into Function)
Annotation: Here, we analyzed the abundances of all splice variants for each alternatively spliced gene in an Arabidopsis mutant that lacks UPF3, one of the core components of NMD machinery, to determine if the PTC-containing transcripts are degraded by NMD.
Organism: A. thaliana
Gene: UPF3
PubMed Id: 19863731
Protein Domain
Protein Domain
Protein Domain
Gene
Length: 1616  
Chromosome Location: Chr5: 23554386-23556001
Organism . Short Name: A. thaliana
TAIR Computational Description: transthyretin-like protein;(source:Araport11)
TAIR Curator Summary: Encodes a transthyretin-like S-allantoin synthase protein that catalyzes two steps in the allantoin biosynthesis pathway by acting as a hydroxyisourate hydrolase and a 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase. Two alternatively spliced versions of the transcript give rise to a longer peroxisomally-targeted protein (AT5G58220.1 (called TTL1-)) and a slightly shorter cytoplasmic protein (AT5G58220.3 (called TTL2-)). Both have roughly equivalent enzymatic activity in vitro, but, allantoin biosynthesis is believed to occur in the peroxisome suggesting that the cytosolic form may participate in a different process.
TAIR Short Description: transthyretin-like protein
TAIR Aliases: ALNS, TTL
Publication
First Author: Koch N
Title: Primary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin.
Year: 1987
Journal: EMBO J
Volume: 6
Pages: 1677-83
Protein Domain
SO Term
Description: A self spliced intron.
SO Term
Description: A gene with a transcript that is trans-spliced.
Ontology Term Synonym
Name: gene with trans spliced transcript
Type: synonym
Protein Domain
Protein Domain
Gene
Length: 1236  
Chromosome Location: Chr3: 9827682-9828917
Organism . Short Name: A. thaliana
TAIR Computational Description: CCR-like protein;(source:Araport11)
TAIR Curator Summary: transcripts are differentially regulated at the level of mRNA stability at different times of day controlled by the circadian clock. mRNAs are targets of the mRNA degradation pathway mediated by the downstream (DST) instability determinant.
TAIR Short Description: CCR-like
TAIR Aliases: CCL
Protein Domain
Protein Domain
GO Term
Description: A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins.
Gene
Length: 1389  
Chromosome Location: Chr4: 16944878-16946266
Organism . Short Name: A. thaliana
TAIR Computational Description: Rhodanese/Cell cycle control phosphatase superfamily protein;(source:Araport11)
TAIR Curator Summary: Senescence-associated gene that is strongly induced by phosphate starvation. Transcripts are differentially regulated at the level of mRNA stability at different times of day. mRNAs are targets of the mRNA degradation pathway mediated by the downstream (DST) instability determinant.
TAIR Short Description: Rhodanese/Cell cycle control phosphatase superfamily protein
TAIR Aliases: ATSEN1, DIN1, SAG1, SEN1
Gene
Length: 1220  
Chromosome Location: Chr1: 30133718-30134937
Organism . Short Name: A. thaliana
TAIR Computational Description: histidine phosphotransfer protein 6;(source:Araport11)
TAIR Curator Summary: AHP6 lacks the conserved histidine residue (Asn83 in AHP6b), which is required for phosphotransfer, present in the other AHPs. AHP6 does not appear to have phosphotransfer activity. Acts as an inhibitor of cytokinin signaling by interacting with the phosphorelay machinery. Expressed in developing protoxylem and associated pericycle cell files. Negative regulator of cytokinin signaling. Expression is down-regulated by cytokinins. There are two alternatively spliced genes for this locus, AHP6a and AHP6b, differing in the length of the first exon. In ahp6-2 seedlings, only the AHP6a transcript is present. Members of the AHP gene family include: AT3G21510 (AHP1), AT3G29350 (AHP2), AT5G39340 (AHP3), AT3G16360 (AHP4), AT1G03430 (AHP5) and AT1G80100 (AHP6).
TAIR Short Description: histidine phosphotransfer protein 6
TAIR Aliases: AHP6, HP6
Protein Domain
Protein Domain
Gene
Length: 1464  
Chromosome Location: Chr5: 4149738-4151201
Organism . Short Name: A. thaliana
TAIR Computational Description: WRKY DNA-binding protein 75;(source:Araport11)
TAIR Curator Summary: WRKY75 is one of several transcription factors induced during Pi deprivation. It is nuclear localized and regulated differentially during Pi starvation. RNAi mediated suppression of WRKY75 made the plants more susceptible to Pi stress as indicated by the higher accumulation of anthocyanin during Pi starvation.
TAIR Short Description: WRKY DNA-binding protein 75
TAIR Aliases: ATWRKY75, WRKY75