Encodes a microRNA that targets several PPR family members. MicroRNAs are regulatory RNAs with a mature length of ~21-nucleotides that are processed from hairpin precursors by Dicer-like enzymes. MicroRNAs can negatively regulate gene expression by attenuating translation or by directing mRNA cleavage.Mature sequence: UCAAUGCAUUGAAAGUGACUA. Pri-mRNA coordinates for MIR161 (converted to TAIR10 based on PMID19304749): Chr4: 17825619-17826317 (forward), length: 699 bp; exon coordinates: exon 1: 17825619 to 17825867, exon 2: 17825996 to 17826317; mature miRNA and miRNA* are located on exon 1.