Do plants have versions of human genes?
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In this lesson, students will utilize bioinformatics tools and concepts to propose a plant model that might prove useful in studying a human genetic disease. In Part A, students Engage prior knowledge of genetics and human diseases using the Online Mendelian Inheritance in Man portal (www.OMIM.org) to identify a sample gene which has a role in a human disease. They will briefly write to expose their preconceptions of scientific models and of processes which are common to both plants and humans. They next Explore using bioinformatics tools. Students will find information about the sample human disease gene from the www.NCBI.nlm.nih.gov portal. Students will use the BLASTn tool to align the human gene DNA sequence with Arabidopsis thaliana DNA sequences in order to identify names of prospective plant versions of the human gene. They will learn to decipher the BLASTn report results in order to identify the most
|The Arabidopsis Biological Resource Center has over 400,000 seed lines and over 400,000 DNA resources in its collection related to the model organism, Arabidopsis thaliana ...|
|In 2010, recognizing that there was a gap in plant biology knowledge in students of all ages, from kindergarten to the undergraduate college level, ABRC introduced education modules containing Arabidopsis seeds and DNA stocks to students and teachers for the first time. These education modules are designed to develop students understanding of concepts such as Mendelian inheritance, gene expression, and natural selection, and were created by ABRC and multiple collaborators. Teachers and parents can order seeds and DNA stocks as well as download protocols and other resources at http://abrcoutreach.osu.edu. All charges for these resources are waived for K-12 students and teachers.|