Encodes a pentapeptide-repeat protein (PRP) composed of 25 repeats capped by N- and C-terminal a-helices. Unlike other PRPs, At2g44920 consists exclusively of type II b-turns
TAIR Short Description:
Tetratricopeptide repeat (TPR)-like superfamily protein
structure of At2g44920 consists of the characteristic repeated five-residue fold with five uninterrupted coils made up of 25 pentapeptide repeats and alpha-helical elements capping both termini
At2g44920 represents an extremely well-defined model system for investigating amide exchange rates in proteins, and it exhibits a remarkable range of exchange lifetimes spanning 10 orders of magnitude. Results illustrate that consideration of activation energies of amide hydrogen exchange adds important insight into understanding and predicting amide hydrogen protection factors in proteins.